Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467039 | 0.77 | — | — | |
| SCHEMBL2788221 | 0.77 | PLA2G1B (0.39) | LMNAMAPT | |
| SCHEMBL476608 | 0.76 | DNM1 (0.40) | DNM1HIF1ALMNASMN1; SMN2HTT | |
| SCHEMBL1204653 | 0.76 | DNM1 (0.34) | DNM1HIF1ALMNASMN1; SMN2HTT | |
| SCHEMBL13043954 | 0.76 | DNM1 (0.34) | DNM1HIF1ALMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28910390 | 0.75 | — | — | |
| SCHEMBL6263042 | 0.74 | DNM1 (0.33) | DNM1HIF1ALMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL10686188 | 0.74 | HIF1A (0.43) | DNM1HIF1ALMNASMN1; SMN2HTT | |
| SCHEMBL689269 | 0.72 | — | — | |
| SCHEMBL14888870 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314873-B2 | (Halo-benzo carbonyl)heterobi cyclic p38 linase inhibiting agents | MERCK & CO., INC. (US) | 2008-01-01 | — | — | US | disclosed |
| EP-1654236-A1 | NAPHTHYLENE DERIVATIVES AS CYTOCHROME P450 INHIBITORS | OSI Pharmaceuticals, Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005007631-A1 | NAPHTHYLENE DERIVATIVES AS CYTOCHROME P450 INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2005-01-27 | — | — | WO | disclosed |