SCHEMBL689269

SCHEMBL689269

CN(C)CC(O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14888870 1.00
SCHEMBL6534348 1.00
Hydrochloric Acid SCHEMBL14311845 0.97 HIF1A (0.38)
Hydrochloric Acid SCHEMBL14342907 0.97
Hydrochloric Acid SCHEMBL14311823 0.97 HIF1A (0.38)
SCHEMBL21544070 0.85 LMNA (0.36)
SCHEMBL16384342 0.82 GABRR1 (0.37)
SCHEMBL16384343 0.82 GABRR1 (0.37)
Trifluoroacetic Acid SCHEMBL30253399 0.81 GABRR1 (0.39)
SCHEMBL476608 0.81 DNM1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105705489-B Compound as immunomodulator 百时美施贵宝公司 2019-04-26 CN claimed
EP-3041822-A1 COMPOUNDS USEFUL AS IMMUNOMODULATORS Bristol-Myers Squibb Company (US) 2016-07-13 EP claimed
CN-105705489-A Compounds useful as immunomodulators 百时美施贵宝公司 2016-06-22 CN claimed
WO-2015034820-A1 COMPOUNDS USEFUL AS IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2015-03-12 WO claimed
CN-100415724-C Pyrimidine derivatives ASTRAZENECA AB (SE) 2008-09-03 CN claimed
CN-100352804-C Amide derivatives ASTRAZENECA AB (SE) 2007-12-05 CN claimed
US-7060700-B2 Amide derivatives useful as inhibitors of the production of cytokines ASTRAZENECA AB (SE) 2006-06-13 US claimed
EP-1163212-B1 AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2005-08-31 EP claimed
US-6846827-B1 Pyrimidine derivatives ASTRAZENECA AB (SE) 2005-01-25 US claimed
EP-1226126-B1 PYRIMIDINE DERIVATIVES ASTRAZENECA AB (SE) 2005-01-05 EP claimed
EP-1226126-A1 PYRIMIDINE DERIVATIVES AstraZeneca AB (SE) 2002-07-31 EP claimed
CN-1344249-A Amide derivatives ASTRAZENECA AB (SE) 2002-04-10 CN claimed
EP-1163212-A1 AMIDE DERIVATIVES AstraZeneca AB (SE) 2001-12-19 EP claimed
CN-1321150-A Amide derivs. useful as inhibitors of production of cytokines ASTRAZENECA AB (SE) 2001-11-07 CN claimed
EP-1115707-A1 BENZAMIDE DERIVATIVES AND THER USE AS CYTOKINE INHIBITORS AstraZeneca AB (SE) 2001-07-18 EP claimed
EP-1102750-A1 AMIDE DERIVATIVES USEFUL AS INHIBITORS OF THE PRODUCTION OF CYTOKINES AstraZeneca AB (SE) 2001-05-30 EP claimed
WO-2001027089-A1 PYRIMIDINE DERIVATIVES ASTRAZENECA AB (SE) 2001-04-19 WO claimed
WO-2000055120-A1 AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2000-09-21 WO claimed
WO-2000018738-A1 BENZAMIDE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS ASTRAZENECA AB (SE) 2000-04-06 WO claimed
WO-2000007991-A1 AMIDE DERIVATIVES USEFUL AS INHIBITORS OF THE PRODUCTION OF CYTOKINES ASTRAZENECA AB (SE) 2000-02-17 WO claimed