SCHEMBL48592

SCHEMBL48592

Cc1csc(N)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9185862 0.97
Hydrochloric Acid SCHEMBL1966505 0.97
Hydrochloric Acid SCHEMBL4139462 0.97
SCHEMBL7026518 0.87 SMN1; SMN2 (0.75)
SCHEMBL17407204 0.82 SMN1; SMN2 (0.68)
SCHEMBL27769476 0.82 SMN1; SMN2 (0.67)
SCHEMBL6711413 0.82 SMN1; SMN2 (0.67)
Hydrochlorthiazide SCHEMBL27606153 0.80 SMN1; SMN2 (0.64)
SCHEMBL11505502 0.80 ALDH1A1 (0.79)
SCHEMBL10719025 0.73 ALDH1A1 (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2847 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569723-A Bactericide for oil field and synthetic method and application thereof 东营施普瑞石油工程技术有限公司 2025-03-07 CN claimed
CN-119194545-A Silver plating process for integrated circuit lead frame 崇辉半导体(江门)有限公司 2024-12-27 CN claimed
CN-118871112-A Use of 4-thiazol-N- (pyridin-2-yl) pyrimidin-2-amine derivatives in cancer combination therapy 澳升医药公司 2024-10-29 CN claimed
CN-113881509-B Pore-forming agent and preparation method thereof 深圳市励高表面处理材料有限公司 2024-06-07 CN claimed
US-RE49850-E1 N-(pyridin-2-yl)-4-(thiazol-5-yl)pyrimidin-2-amine derivatives as therapeutic compounds AUCENTRA THERAPEUTICS PTY LTD (AU) 2024-02-27 US claimed
CN-117285546-A Imidazothiazole modified naphthalimide-polyamine conjugates, methods of preparation and uses 河南大学 2023-12-26 CN claimed
CN-117285922-A Integrated variable-viscosity fracturing fluid and preparation method thereof 山东普瑞思德石油技术有限公司 2023-12-26 CN claimed
CN-117209448-A Process for the preparation of (benzo) thiazole-containing thio/selenoacetamides and derivatives thereof 济宁医学院 2023-12-12 CN claimed
CN-117126119-A Preparation method of (benzo) thiazole amide-containing compound 济宁医学院 2023-11-28 CN claimed
CN-115666561-A Treatment of proliferative diseases of the CNS 澳升医药公司 2023-01-31 CN claimed
EP-0153709-B1 NOVEL CEPHALOSPORIN DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 1991-08-14 EP claimed
US-4785090-A ANTIBIOTICS, BACTERICIDES MEIJI SEIKA KAISHA, LTD. (JP) 1988-11-15 US claimed
EP-0096319-B1 METHOD FOR PREVENTING SCALE DEPOSITION IN THE POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS Shin-Etsu Chemical Co., Ltd. (JP) 1986-03-26 EP claimed
EP-0153709-A2 Novel cephalosporin derivatives MEIJI SEIKA KAISHA LTD. (JP) 1985-09-04 EP claimed
US-4496727-A ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS CIBA-GEIGY CORPORATION (US) 1985-01-29 US claimed
US-4384929-A THIAZOLE COMPOUND PROVIDES THE SPECIFIED SULFUR CONTENT OCCIDENTAL CHEMICAL CORPORATION (US) 1983-05-24 US claimed
US-4385174-A FOR PIGMENTS CIBA-GEIGY CORPORATION (US) 1983-05-24 US claimed
US-4349671-A Process for the production of metal complexes of isoindoline azines CIBA-GEIGY CORPORATION (US) 1982-09-14 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-3933498-A Fogged, direct positive silver halide emulsions containing a bleach inhibiting compound and a Dmin maintainer compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 US claimed