Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | NOS1 | P29475 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48592 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1966505 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL4139462 | 0.80 | — | — | |
| Water SCHEMBL9185862 | 0.80 | — | — | |
| SCHEMBL7026518 | 0.75 | SMN1; SMN2 (0.75) | SMN1; SMN2NOS1ALDH1A1MAPTMEN1 | |
| SCHEMBL27742441 | 0.73 | GABRA5 (0.60) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1000856 | 0.72 | ALDH1A1 (0.44) | SMN1; SMN2NOS1ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11102564 | 0.70 | ALDH1A1 (0.46) | SMN1; SMN2NOS1ALDH1A1MAPTMEN1 | |
| SCHEMBL965863 | 0.68 | — | — | |
| SCHEMBL354383 | 0.68 | GABRA5 (0.54) | SMN1; SMN2NOS1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101627019-B | Bicyclic pyrimidinones and uses thereof | AVEXA LTD | 2013-07-10 | — | — | CN | disclosed |
| CN-101880280-A | Bicyclic pyrimidinones and uses thereof | SHANGHAI INST ORGANIC CHEM | 2010-11-10 | — | — | CN | disclosed |
| CN-101627019-A | Bicyclic pyrimidinones and uses thereof | AVEXA LTD | 2010-01-13 | — | — | CN | disclosed |