Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237517 | 0.95 | CCR3 (0.45) | CCR3MCHR1FGFR1MAPTHPGD | |
| SCHEMBL4745650 | 0.93 | CCR3 (0.37) | CCR3MCHR1MAPTHPGDTSHR | |
| SCHEMBL4234129 | 0.92 | MCHR1 (0.42) | CCR3MCHR1FGFR1MAPTHPGD | |
| SCHEMBL4229363 | 0.92 | PKM (0.39) | MCHR1MAPTTSHRHSD17B10MEN1 | |
| SCHEMBL4236062 | 0.86 | MCHR1 (0.47) | MCHR1FGFR1MAPTMEN1KMT2A | |
| SCHEMBL4233894 | 0.86 | MCHR1 (0.47) | MCHR1FGFR1MAPTMEN1KMT2A | |
| SCHEMBL4233712 | 0.85 | MAPT (0.38) | CCR3MCHR1MAPTHPGDTSHR | |
| SCHEMBL4242394 | 0.85 | TAS1R3 (0.43) | MCHR1MAPTTSHRHSD17B10MEN1 | |
| SCHEMBL4229397 | 0.85 | MCHR1 (0.44) | MCHR1MAPTMEN1KMT2A | |
| SCHEMBL4240513 | 0.84 | MCHR1 (0.40) | MCHR1MAPTHPGDTSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |