Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HLCS | P50747 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11654109 | 0.79 | KMT2A (0.48) | MAPTALDH1A1 | |
| SCHEMBL16014923 | 0.78 | CYP1A2 (0.37) | MAPTPOLBNPSR1FAAHMGLL | |
| SCHEMBL6827759 | 0.76 | KMT2A (0.41) | MAPTPOLBNPSR1ALDH1A1 | |
| SCHEMBL11727538 | 0.75 | PTGER4 (0.57) | — | |
| SCHEMBL11727526 | 0.75 | PTGER4 (0.57) | — | |
| SCHEMBL11727535 | 0.75 | PTGER4 (0.57) | — | |
| SCHEMBL5852489 | 0.75 | PTGER4 (0.57) | — | |
| SCHEMBL11659856 | 0.75 | PTGER4 (0.66) | FAAH | |
| SCHEMBL6829809 | 0.75 | PIM1 (0.45) | MAPTPOLBNPSR1TP53CYP1A2 | |
| SCHEMBL5854450 | 0.74 | PTGER4 (0.39) | MAPTPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786493-B | 2,3-diaryl thiazolidinone compound and analogue, and purpose thereof in preparing antiangiogenic drugs | EAST CHINA NORMAL UNIVERSITY (CN) | 2014-10-01 | — | — | CN | disclosed |
| CN-102786493-B | 2,3-diaryl thiazolidinone compound and analogue, and purpose thereof in preparing antiangiogenic drugs | EAST CHINA NORMAL UNIVERSITY (CN) | 2014-10-01 | — | — | CN | disclosed |
| CN-102786493-A | 2,3-diaryl thiazolidinone compound and analogue, and purpose thereof in preparing antiangiogenic drugs | UNIV EAST CHINA NORMAL | 2012-11-21 | — | — | CN | disclosed |
| CN-102786493-A | 2,3-diaryl thiazolidinone compound and analogue, and purpose thereof in preparing antiangiogenic drugs | UNIV EAST CHINA NORMAL | 2012-11-21 | — | — | CN | disclosed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |