Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829809 | 0.79 | PIM1 (0.45) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL5152787 | 0.76 | KMT2A (0.42) | KMT2AMEN1MAPTALDH1A1HTR7 | |
| SCHEMBL4859563 | 0.76 | MAPT (0.47) | MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL16014923 | 0.68 | CYP1A2 (0.37) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL5153105 | 0.64 | KMT2A (0.58) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL5152239 | 0.64 | MAPT (0.58) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL9488035 | 0.64 | GRM2 (0.39) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL6919581 | 0.63 | MEN1 (0.65) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL5156737 | 0.62 | KMT2A (0.61) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL9224226 | 0.61 | MEN1 (0.38) | KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017965-A1 | 1,3-THIAZOLIN-4-ONES AS THERAPEUTIC COMPOUNDS IN THE TREATMENT OF PAIN | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |