Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824863 | 0.81 | PIM1 (0.46) | PIM1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6827759 | 0.79 | KMT2A (0.41) | KMT2AMEN1ALDH1A1GRM2POLB | |
| SCHEMBL5156138 | 0.79 | PIM1 (0.46) | PIM1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL4859563 | 0.75 | MAPT (0.47) | ALDH1A1POLBMAPTNPSR1TP53 | |
| SCHEMBL5152891 | 0.74 | PIM1 (0.44) | PIM1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL5152147 | 0.72 | MEN1 (0.65) | PIM1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL746037 | 0.71 | MEN1 (0.56) | PIM1KMT2AMEN1NPSR1ACHE | |
| SCHEMBL745499 | 0.70 | HCRTR2 (0.62) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9488035 | 0.68 | GRM2 (0.39) | KMT2AMEN1ALDH1A1GRM2POLB | |
| SCHEMBL2821971 | 0.68 | GRM2 (0.64) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017965-A1 | 1,3-THIAZOLIN-4-ONES AS THERAPEUTIC COMPOUNDS IN THE TREATMENT OF PAIN | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |