SCHEMBL4859931

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5113671	0.85	APP (0.74)	APPCDK2CCNE2CCNE1MEN1
	SCHEMBL4863308	0.85	APP (0.68)	APPCDK2CCNE2CCNE1MEN1
	SCHEMBL4863048	0.84	APP (0.66)	APPMEN1KMT2ABCHEACHE
	SCHEMBL5107781	0.83	APP (0.71)	APPCDK2CCNE2CCNE1MEN1
	SCHEMBL4864021	0.81	APP (0.73)	APPCDK2CCNE2CCNE1MEN1
	SCHEMBL4866870	0.81	APP (0.73)	APPCDK2CCNE2CCNE1MEN1
	SCHEMBL4863323	0.81	APP (0.71)	APPMEN1KMT2ABCHEACHE
	SCHEMBL4868511	0.80	APP (0.67)	APPCDK2CCNE2CCNE1MEN1
	SCHEMBL9430554	0.77	EGFR (0.69)	APPCDK2CCNE2CCNE1MAPK1
	SCHEMBL4867671	0.77	PDE5A (0.69)	APPCDK2CCNE2CCNE1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.