Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23227891 | 1.00 | TSHR (0.52) | TSHRALDH1A1NAAAKDM4EPOLB | |
| SCHEMBL5349731 | 1.00 | TSHR (0.52) | TSHRALDH1A1NAAAKDM4EPOLB | |
| SCHEMBL8743578 | 0.98 | TSHR (0.54) | TSHRALDH1A1NAAAKDM4EPOLB | |
| SCHEMBL8157722 | 0.88 | ALDH1A1 (0.61) | TSHRALDH1A1KDM4EPOLBTACR1 | |
| SCHEMBL8743637 | 0.85 | TSHR (0.52) | TSHRALDH1A1NAAAKDM4EPOLB | |
| SCHEMBL27710140 | 0.83 | TSHR (0.74) | TSHRNAAAKDM4EPOLBTACR1 | |
| SCHEMBL9505432 | 0.83 | TSHR (0.74) | TSHRNAAAKDM4EPOLBTACR1 | |
| SCHEMBL10895400 | 0.83 | TSHR (0.74) | TSHRNAAAKDM4EPOLBTACR1 | |
| SCHEMBL4608747 | 0.83 | TSHR (0.74) | TSHRNAAAKDM4EPOLBTACR1 | |
| SCHEMBL26189828 | 0.83 | TSHR (0.74) | TSHRNAAAKDM4EPOLBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354966-B2 | Non-fluorinated or low fluorine content internal salts of glycerol 2-aminoethyl phosphates; use in aerosols for inhalants for treating asthma, chronic obstructive pulmonary disease and rhinitis | GLAXO GROUP LIMITED (GB) | 2008-04-08 | — | — | US | disclosed |
| US-7217409-B2 | Alkanoic acid derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-15 | — | — | US | disclosed |
| US-20050287076-A1 | Compounds for use as surfactants | GLAXO GROUP LIMITED (GB) | 2005-12-29 | — | — | US | disclosed |
| EP-1480990-B1 | COMPOUNDS FOR USE AS SURFACTANTS | GLAXO GROUP LTD (GB) | 2005-11-09 | — | — | EP | disclosed |
| EP-1480990-A1 | COMPOUNDS FOR USE AS SURFACTANTS | GLAXO GROUP LIMITED (GB) | 2004-12-01 | — | — | EP | disclosed |
| US-20040067202-A1 | Novel alkanoic acid derivaties | GLAXO GROUP LIMITED (GB) | 2004-04-08 | — | — | US | disclosed |
| WO-2003074537-A1 | COMPOUNDS FOR USE AS SURFACTANTS | GLAXO GROUP LIMITED (GB) | 2003-09-12 | — | — | WO | disclosed |
| EP-1318973-A2 | NOVEL ALKANOIC ACID DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024623-A2 | NOVEL ALKANOIC ACID DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067202-A1 | Novel alkanoic acid derivaties | ALK, FFAR1, FFAR3 | TSHR 2123/4885ALDH1A1 87/4885NAAA 1409/4885 |
| US-20050287076-A1 | Compounds for use as surfactants | SGMS1, SGMS2, PHOSPHO1 | TSHR 4053/4885ALDH1A1 1584/4885NAAA 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.