Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84523 | 0.98 | KCNH2 (0.40) | KCNH2GPR84CNR1CNR2DGAT1 | |
| SCHEMBL15057850 | 0.93 | MEN1 (0.38) | KCNH2GPR84DGAT1TDP1L3MBTL1 | |
| SCHEMBL27457526 | 0.85 | NOS2 (0.36) | TDP1L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL27769288 | 0.80 | KCNH2 (0.58) | KCNH2GPR84TDP1L3MBTL1ESR1 | |
| SCHEMBL27634918 | 0.80 | KCNH2 (0.44) | KCNH2GPR84TDP1L3MBTL1ESR1 | |
| SCHEMBL27977748 | 0.80 | KCNH2 (0.58) | KCNH2GPR84TDP1L3MBTL1ESR1 | |
| SCHEMBL11310160 | 0.80 | KCNH2 (0.44) | KCNH2GPR84TDP1L3MBTL1ESR1 | |
| SCHEMBL11334282 | 0.79 | KCNH2 (0.43) | KCNH2GPR84TDP1L3MBTL1ESR1 | |
| SCHEMBL29172695 | 0.79 | KCNH2 (0.43) | KCNH2GPR84ADORA3KDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28527210 | 0.79 | KCNH2 (0.56) | KCNH2GPR84DGAT1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888138-B1 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | ABIOMED INC (US) | 2013-09-04 | — | — | EP | claimed |
| JP-2008544769-A | — | — | 2008-12-11 | — | — | JP | claimed |
| EP-1888138-A2 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | Abiomed, Inc. (US) | 2008-02-20 | — | — | EP | claimed |
| WO-2006121908-A2 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | ABIOMED, INC. (US) | 2006-11-16 | — | — | WO | claimed |
| US-20060257355-A1 | Impregnated polymer compositions and devices using them | ABIOMED, INC. (US) | 2006-11-16 | — | — | US | claimed |
| EP-1888138-B1 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | ABIOMED INC (US) | 2013-09-04 | — | — | EP | disclosed |
| EP-1888138-A2 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | Abiomed, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006121908-A2 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | ABIOMED, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| US-20060257355-A1 | Impregnated polymer compositions and devices using them | ABIOMED, INC. (US) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060257355-A1 | Impregnated polymer compositions and devices using them | CD47, CD99, FGB | KCNH2 4243/4885GPR84 2573/4885CNR1 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.