Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003601 | 0.92 | ALDH1A1 (0.58) | TSHRTDP1KMT2AALDH1A1PKM | |
| SCHEMBL853943 | 0.82 | KMT2A (0.62) | TSHRTDP1KMT2AALDH1A1PKM | |
| SCHEMBL111537 | 0.81 | TSHR (0.73) | TSHRTDP1KMT2AALDH1A1PKM | |
| Methoxymethane SCHEMBL7082256 | 0.81 | TSHR (0.61) | TSHRTDP1KMT2AALDH1A1PKM | |
| SCHEMBL29390085 | 0.81 | TSHR (0.73) | TSHRTDP1KMT2AALDH1A1PKM | |
| SCHEMBL6277917 | 0.81 | ALDH1A1 (0.41) | KMT2AALDH1A1PKMMEN1MAPT | |
| SCHEMBL29390514 | 0.79 | KMT2A (0.70) | TSHRTDP1KMT2AALDH1A1PKM | |
| SCHEMBL126989 | 0.79 | KMT2A (0.70) | TSHRTDP1KMT2AALDH1A1PKM | |
| SCHEMBL900753 | 0.79 | MAPT (0.66) | KMT2AALDH1A1MEN1MAPTHTT | |
| SCHEMBL9682978 | 0.79 | KMT2A (0.65) | TSHRTDP1KMT2AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
| EP-1568355-A1 | N-alkylhydroxilated secondary paraphenylenediamine which is ortho- and/or meta substituted, composition for dying keratinous fibres comprising this paraphenylenediamine, methods based on this composition and uses. | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | KRT18, CDC73, TYR | TSHR 4206/4885TDP1 1822/4885KMT2A 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.