Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MYOC | Q99972 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859122 | 0.78 | MEN1 (0.69) | HTTNR1H4PTGS2MEN1KMT2A | |
| SCHEMBL30176238 | 0.78 | HTT (0.58) | HTTNR1H4HSPB1MEN1KMT2A | |
| SCHEMBL14280534 | 0.78 | NPSR1 (0.41) | HTTPTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL28051442 | 0.77 | HSPB1 (0.70) | HTTHSPB1MCL1MEN1KMT2A | |
| SCHEMBL3208134 | 0.77 | HSPB1 (0.70) | HTTHSPB1MCL1MEN1KMT2A | |
| SCHEMBL4857603 | 0.76 | ALDH1A1 (0.50) | NR1H4PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL30176239 | 0.75 | HTT (0.54) | HTTNR1H4HSPB1MEN1KMT2A | |
| SCHEMBL15858620 | 0.74 | HSPB1 (0.53) | HTTHSPB1MEN1KMT2AALDH1A1 | |
| SCHEMBL28983411 | 0.73 | HSPB1 (0.51) | HTTNR1H4HSPB1PTGS2MEN1 | |
| SCHEMBL4670068 | 0.73 | HSPB1 (0.59) | HTTHSPB1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317110-B2 | Low dielectric constant organo-soluble polyimides | HOME SUN INDUSTRIAL CO., LTD. (TW) | 2008-01-08 | — | — | US | disclosed |
| US-20060178499-A1 | Low dielectric constants organic-soluble polyimides, and method for manufacturing thereof | HOME SUN INDUSTRIAL CO,. LTD. (TW) | 2006-08-10 | — | — | US | disclosed |