Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MGAM | O43451 | 2/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.51 |
| ▸ | SI | P14410 | 2/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979383 | 0.84 | HPGD (0.69) | RAB9AGAAMGAMAMY1ASI | |
| SCHEMBL23209625 | 0.81 | RAB9A (0.49) | RAB9AGAAMGAMAMY1ASI | |
| SCHEMBL21793669 | 0.74 | KMT2A (0.55) | RAB9AGAANPC1MAPTLMNA | |
| SCHEMBL23232864 | 0.74 | RAB9A (0.60) | RAB9AGAAMGAMAMY1ASI | |
| SCHEMBL4861387 | 0.73 | MGAM (0.58) | RAB9AGAAMGAMAMY1ASI | |
| SCHEMBL6556649 | 0.72 | MAPT (0.48) | RAB9AGAAMGAMAMY1ASI | |
| SCHEMBL11530650 | 0.70 | KDR (0.53) | RAB9AGAAMGAMAMY1ASI | |
| SCHEMBL17504554 | 0.69 | MEN1 (0.65) | GAAHPGDALDH1A1MAPTHTT | |
| SCHEMBL24139129 | 0.68 | NPC1 (0.62) | RAB9AGAAMGAMAMY1ASI | |
| SCHEMBL23209619 | 0.68 | HPGD (0.48) | RAB9AGAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345009-B2 | Reacting 4-phenyl pyraoline compound with phenyl isocyanate compound | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7345009-B2 | Reacting 4-phenyl pyraoline compound with phenyl isocyanate compound | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | MAURER FRITZ | 2008-03-13 | — | — | US | disclosed |
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | MAURER FRITZ | 2008-03-13 | — | — | US | disclosed |
| CN-1646521-A | Substituted 4-heteroarylpyrazolines as pest control agents | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | CN | disclosed |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | BAYER CROPSCIENCE AG (DE) | 2005-06-02 | — | — | US | disclosed |
| EP-1474418-A1 | SUBSTITUTED 4-HETARYL-PYRAZOLINES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066625-A1 | SUBSTITUTED 4-HETARYL-PYRAZOLINES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | CYP4F3, CYP4X1, CYP4B1 | RAB9A 363/4885GAA 2737/4885MGAM 3256/4885 |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | CYP4X1, CYP4F3, DDT | RAB9A 235/4885GAA 3526/4885MGAM 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.