Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | SI | P14410 | 4/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979378 | 0.84 | MGAM (0.56) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL21826430 | 0.81 | POLB (0.55) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL4860671 | 0.73 | RAB9A (0.54) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL11710847 | 0.71 | MAPK1 (0.62) | GAANPC1MAPTALDH1A1MAPK1 | |
| SCHEMBL18496481 | 0.71 | ALDH1A1 (0.53) | GAARAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24779795 | 0.71 | MAPT (0.77) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL10875398 | 0.70 | NOS1 (0.67) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL2205869 | 0.70 | LMNA (0.47) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL11620173 | 0.70 | MAPK1 (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL8947260 | 0.68 | ALDH1A1 (0.73) | ALDH1A1HTTLMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345009-B2 | Reacting 4-phenyl pyraoline compound with phenyl isocyanate compound | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | MAURER FRITZ | 2008-03-13 | — | — | US | disclosed |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | BAYER CROPSCIENCE AG (DE) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | CYP4F3, CYP4X1, CYP4B1 | MGAM 3256/4885AMY1A 444/4885GAA 2737/4885 |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | CYP4X1, CYP4F3, DDT | MGAM 3591/4885AMY1A 437/4885GAA 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.