Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200838 | 0.83 | MAPKAPK2 (0.36) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL28133648 | 0.81 | MAPKAPK2 (0.35) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL6709123 | 0.77 | CYP1A2 (0.43) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL28007568 | 0.76 | GABRR1 (0.42) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL27887048 | 0.74 | GABRR1 (0.50) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL4520765 | 0.74 | GABRR1 (0.41) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL27598251 | 0.74 | GABRR1 (0.41) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL6932734 | 0.74 | KDM4E (0.49) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7125421 | 0.72 | GABRA5 (0.47) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL27517892 | 0.72 | ATR (0.43) | GABRA5GABRB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343556-A | Bio-based compound modified cracking carbon black and application thereof in tire preparation | 中策橡胶集团股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117247639-A | Tire inner liner rubber composition containing bio-based modified cracking carbon black, mixing method and tire | 中策橡胶集团股份有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117247608-A | Tire pad rubber composition containing bio-based modified cracking carbon black, mixing method and tire | 中策橡胶集团股份有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-116426219-A | Chemical mechanical polishing solution and application thereof | 安集微电子科技（上海）股份有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-114686112-A | Chemical mechanical polishing solution and use method thereof | 安集微电子科技（上海）股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-118076632-A | Conditionally active proteins for neurodegenerative diseases | 生物蛋白有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117343556-A | Bio-based compound modified cracking carbon black and application thereof in tire preparation | 中策橡胶集团股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117247639-A | Tire inner liner rubber composition containing bio-based modified cracking carbon black, mixing method and tire | 中策橡胶集团股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117247608-A | Tire pad rubber composition containing bio-based modified cracking carbon black, mixing method and tire | 中策橡胶集团股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-116426219-A | Chemical mechanical polishing solution and application thereof | 安集微电子科技（上海）股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116143826-A | Novel boron liposome helpful for diagnosis and treatment | 北京大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-112513081-A | Multispecific antibody constructs | 生物蛋白有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-105579447-A | Ethynyl derivatives | HOFFMANN LA ROCHE | 2016-05-11 | — | — | CN | disclosed |
| CN-105385282-A | Environment-friendly fixation paint | TIANJIN SHENGTONG TECH CO LTD | 2016-03-09 | — | — | CN | disclosed |
| CN-102264721-B | Compounds useful as inhibitors of ATR kinase | VERTEX PHARMACEUTICALS INC. (US) | 2015-12-09 | — | — | CN | disclosed |
| CN-104936953-A | Compound (I) | ASTRAZENECA AB | 2015-09-23 | — | — | CN | disclosed |
| CN-104557940-A | BCR-ABL kinase inhibitor and application thereof | NANJING SANHOME PHARMACEUTICAL CO LTD | 2015-04-29 | — | — | CN | disclosed |
| CN-104387331-A | Preparation method of pyrazine derivative | Hunan huateng pharmaceutical co ltd | 2015-03-04 | — | — | CN | disclosed |
| US-7456192-B2 | 3β-amino azabicyclooctane heteroaromatic amid derivatives preparation method and therapeutic uses thereof | PIERRE FABRE MEDICAMENT (FR) | 2008-11-25 | — | — | US | disclosed |
| US-20050080085-A1 | Novel 3beta-amino azabicyclooctane heteroaromatic amid derivatives preparation method and therapeutic uses thereof | PIERRE FABRE MEDICAMENT (FR) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080085-A1 | Novel 3beta-amino azabicyclooctane heteroaromatic amid derivatives preparation method and therapeutic uses thereof | AOC3, MAOB, AOC1 | GABRA5 493/4885GABRB2 134/4885GABRP 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.