Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 11/20 | 0.60 |
| ▸ | MMP8 | P22894 | 10/20 | 0.60 |
| ▸ | MMP1 | P03956 | 6/20 | 0.60 |
| ▸ | MMP3 | P08254 | 5/20 | 0.60 |
| ▸ | MMP2 | P08253 | 12/20 | 0.58 |
| ▸ | ACE | P12821 | 2/20 | 0.58 |
| ▸ | MMP14 | P50281 | 2/20 | 0.56 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.56 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | MMP15 | P51511 | 1/20 | 0.56 |
| ▸ | MMP16 | P51512 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.56 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.56 |
| ▸ | MMP17 | Q9ULZ9 | 1/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15902638 | 1.00 | MMP9 (0.60) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL7103470 | 0.86 | ACE (0.65) | MMP9MMP2ACEALOX15ITGB2 | |
| SCHEMBL7103473 | 0.86 | ACE (0.65) | MMP9MMP2ACEALOX15ITGB2 | |
| SCHEMBL16182036 | 0.86 | MMP9 (0.66) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL6577399 | 0.86 | MMP9 (0.66) | MMP9MMP8MMP1MMP3MMP2 | |
| Hydrochloric Acid SCHEMBL6044254 | 0.85 | MMP9 (0.65) | MMP9MMP8MMP1MMP3MMP2 | |
| Hydrochloric Acid SCHEMBL6044250 | 0.85 | MMP9 (0.65) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL25139559 | 0.82 | MMP9 (0.76) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL3787557 | 0.82 | MMP9 (0.72) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL24814079 | 0.82 | MMP9 (0.69) | MMP9MMP8MMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008523082-A | — | — | 2008-07-03 | — | — | JP | claimed |
| EP-1827460-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006063149-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-06-15 | — | — | WO | claimed |
| US-20200095273-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-03-26 | — | — | US | disclosed |
| US-20180258131-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-09-13 | — | — | US | disclosed |
| US-20160159845-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2016-06-09 | — | — | US | disclosed |
| US-20150025220-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-01-22 | — | — | US | disclosed |
| US-8815830-B2 | Nucleosides with antiviral and anticancer activity | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-08-26 | — | — | US | disclosed |
| US-20140213543-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-07-31 | — | — | US | disclosed |
| EP-1827460-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063149-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200095273-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | SLC29A1, TYMP, NTPCR | MMP9 1212/4885MMP8 2487/4885MMP1 2825/4885 |
| US-20160159845-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | TYMP, SLC29A1, NTPCR | MMP9 1527/4885MMP8 2924/4885MMP1 3024/4885 |
| US-20180258131-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | TYMP, SLC29A1, NTPCR | MMP9 1527/4885MMP8 2924/4885MMP1 3024/4885 |
| US-20150025220-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | TYMP, RNASE1, SLC29A1 | MMP9 1235/4885MMP8 2738/4885MMP1 2280/4885 |
| US-20140213543-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | SLC29A1, TYMP, RNASE1 | MMP9 1319/4885MMP8 2681/4885MMP1 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.