Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851255 | 0.86 | ALDH1A1 (0.40) | POLBMAPTALDH1A1LMNAPLA2G1B | |
| SCHEMBL4858357 | 0.78 | MAPT (0.35) | MAPTALDH1A1GAAGSK3B | |
| SCHEMBL4849243 | 0.78 | POLB (0.46) | POLBMAPTALDH1A1GAAGSK3B | |
| SCHEMBL4849212 | 0.77 | POLB (0.38) | POLBMAPTALDH1A1GAAGSK3B | |
| SCHEMBL14263912 | 0.77 | PPARG (0.43) | POLBMAPTALDH1A1LMNAPLA2G1B | |
| SCHEMBL4852508 | 0.75 | ALDH1A1 (0.44) | POLBMAPTALDH1A1LMNAPLA2G1B | |
| SCHEMBL4911932 | 0.75 | PPARG (0.45) | GSK3B | |
| SCHEMBL4850688 | 0.73 | SMN1; SMN2 (0.38) | POLBMAPTALDH1A1GAAGSK3B | |
| SCHEMBL4857318 | 0.73 | MAPT (0.36) | MAPTALDH1A1MAPK1GSK3BADORA1 | |
| SCHEMBL14263905 | 0.72 | HPGD (0.37) | MAPTALDH1A1GSK3BKDM4EMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348334-B2 | Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-03-25 | — | — | US | claimed |