Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857318 | 0.93 | MAPT (0.36) | ALDH1A1P2RY12MAPTGSK3BFAAH | |
| SCHEMBL4849243 | 0.91 | POLB (0.46) | POLBGAAALDH1A1HPGDMAPT | |
| SCHEMBL4858357 | 0.89 | MAPT (0.35) | GAAALDH1A1HPGDP2RY12MAPT | |
| SCHEMBL4855146 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2POLBGAAALDH1A1HPGD | |
| SCHEMBL4849212 | 0.85 | POLB (0.38) | POLBGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL4851255 | 0.85 | ALDH1A1 (0.40) | POLBGAAALDH1A1HPGDMAPT | |
| SCHEMBL4911932 | 0.85 | PPARG (0.45) | GSK3B | |
| SCHEMBL14263905 | 0.82 | HPGD (0.37) | ALDH1A1HPGDHSD17B10P2RY12MAPT | |
| SCHEMBL4911917 | 0.81 | GSK3B (0.38) | SMN1; SMN2ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL4857408 | 0.77 | FAAH (0.37) | SMN1; SMN2POLBGAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348334-B2 | Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-03-25 | — | — | US | claimed |
| US-20030013729-A1 | New monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LTD. | 2003-01-16 | — | — | US | claimed |
| US-7348334-B2 | Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |
| US-7348334-B2 | Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |
| US-20030013729-A1 | New monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LTD. | 2003-01-16 | — | — | US | disclosed |
| WO-2002081454-A1 | DERIVATIVES OF ARYL ACIDS, THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013729-A1 | New monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them | GPR119, FFAR1, FFAR3 | SMN1; SMN2 3836/4885POLB 4027/4885GAA 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.