SCHEMBL4861487

SCHEMBL4861487

CC(=O)N(c1c[nH]c2ccccc12)C(CC(=O)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
MAPT P10636 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
NPC1 O15118 2/20 0.45
ALDH1A1 P00352 2/20 0.45
RAB9A P51151 2/20 0.45
MITF O75030 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
PKM P14618 1/20 0.45
KDM4E B2RXH2 2/20 0.45
APAF1 O14727 1/20 0.45
POLB P06746 1/20 0.45
RECQL P46063 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CDK4 P11802 1/20 0.43
CCND1 P24385 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGAM O43451 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538983 0.74 KDM4E (0.61) LMNAMAPTMEN1KMT2APKM
SCHEMBL468298 0.74 LMNA (0.52) LMNANPSR1MAPTMEN1KMT2A
SCHEMBL839528 0.74 KDM4E (0.68) LMNAMAPTMEN1KMT2APKM
SCHEMBL839527 0.74 KDM4E (0.68) LMNAMAPTMEN1KMT2APKM
SCHEMBL31018783 0.73 KDM4E (0.63) LMNAMAPTMEN1KMT2APKM
SCHEMBL31018781 0.73 KDM4E (0.63) LMNAMAPTMEN1KMT2APKM
SCHEMBL29751962 0.73 KDM4E (0.63) LMNAMAPTMEN1KMT2APKM
SCHEMBL8710225 0.72 MEN1 (0.46) LMNANPSR1MAPTMEN1KMT2A
SCHEMBL8710230 0.72 MEN1 (0.46) LMNANPSR1MAPTMEN1KMT2A
SCHEMBL29773608 0.72 KDM4E (0.61) LMNAMAPTMEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345229-B1 Insect resistant cotton plants DOW AGROSCIENCES LLC (US) 2008-03-18 US disclosed
US-6943282-B1 Insect resistant plants MYCOGEN PLANT SCIENCE, INC. (US) 2005-09-13 US disclosed
EP-0542929-B1 GLYCOGEN BIOSYNTHETIC ENZYMES IN PLANTS CALGENE LLC (US) 2005-08-10 EP disclosed
US-6538181-B1 Methods and compositions which modify the biosynthesis and degradation pathways of reserve polysaccharides in plants; transgenic plants; Amylases; Transferases; Synthases, ADP-Glucose pyrophosphorylase CALGENE LLC 2003-03-25 US disclosed
US-5969214-A TRANSGENIC PLANTS WHICH MODIFY THE BIOSYNTHESIS AND DEGRADATION PATHWAYS OF RESERVE POLYSACCHARIDES IN PLANTS. CALGENE, INC. (US) 1999-10-19 US disclosed
US-5750875-A MODIFICATION OF BIOSYNTHESIS AND DEGRADATION PATHWAYS OF RESERVE POLYSACCHARIDES IN PLANTS MONSANTO COMPANY 1998-05-12 US disclosed
US-5349123-A Glycogen biosynthetic enzymes in plants CALGENE, INC. (US) 1994-09-20 US disclosed
EP-0542929-A4 GLYCOGEN BIOSYNTHETIC ENZYMES IN PLANTS 1993-09-01 EP disclosed
EP-0486683-A4 PRODUCTION OF CYCLODEXTRINS IN TRANSGENIC PLANTS 1993-07-14 EP disclosed
EP-0542929-A1 GLYCOGEN BIOSYNTHETIC ENZYMES IN PLANTS CALGENE, INC. (US) 1993-05-26 EP disclosed
WO-1992011382-A1 GLYCOGEN BIOSYNTHETIC ENZYMES IN PLANTS CALGENE, INC. (US) 1992-07-09 WO disclosed
EP-0486683-A1 PRODUCTION OF CYCLODEXTRINS IN TRANSGENIC PLANTS CALGENE, INC. (US) 1992-05-27 EP disclosed
WO-1991019808-A1 PRODUCTION OF CYCLODEXTRINS IN TRANSGENIC PLANTS CALGENE, INC. (US) 1991-12-26 WO disclosed