Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710225 | 1.00 | MEN1 (0.46) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL26978217 | 0.73 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4861487 | 0.72 | LMNA (0.47) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6394938 | 0.72 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL538983 | 0.70 | KDM4E (0.61) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL7201041 | 0.70 | KDM4E (0.61) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL10980705 | 0.70 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL30735894 | 0.69 | KDM4E (0.64) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL27474102 | 0.69 | LMNA (0.58) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL27777642 | 0.69 | GPR84 (0.56) | MEN1KMT2AALDH1A1MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753619-A | CYCLIC HEPTAPEPTIDES FOR CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INSUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |