Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21926464 | 0.83 | RHOA (0.69) | SMN1; SMN2HPGDRAB9APOLBLMNA | |
| SCHEMBL19002751 | 0.81 | PKM (0.63) | KMT2AHPGDGAALMNATP53BP1 | |
| SCHEMBL7298745 | 0.81 | HPGD (0.69) | KMT2ASMN1; SMN2HPGDRAB9AHTT | |
| SCHEMBL14874212 | 0.81 | PKM (0.63) | KMT2AHPGDGAALMNATP53BP1 | |
| SCHEMBL5870918 | 0.80 | ABL1 (0.62) | KMT2ASMN1; SMN2HPGDRAB9AHTT | |
| SCHEMBL3715390 | 0.80 | ABL1 (0.62) | KMT2ASMN1; SMN2HPGDRAB9AHTT | |
| SCHEMBL30606200 | 0.80 | BCHE (0.50) | KMT2AHPGDRAB9APOLBGAA | |
| SCHEMBL20137614 | 0.77 | YAP1 (0.63) | KMT2ASMN1; SMN2HPGDGAALMNA | |
| SCHEMBL20137868 | 0.77 | YAP1 (0.63) | KMT2ASMN1; SMN2HPGDGAALMNA | |
| SCHEMBL20137615 | 0.77 | YAP1 (0.63) | KMT2ASMN1; SMN2HPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |