Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624148 | 0.92 | MEN1 (0.54) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL393417 | 0.85 | ALDH1A1 (0.48) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL457388 | 0.83 | ALDH1A1 (0.46) | NPC1RAB9AMEN1KMT2ANOX1 | |
| Hydrochloric Acid SCHEMBL9773792 | 0.83 | ALDH1A1 (0.46) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL19937963 | 0.82 | GAA (0.53) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL14223698 | 0.81 | PTPN1 (0.44) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL14223446 | 0.81 | PTPN1 (0.44) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL4854779 | 0.81 | KMT2A (0.58) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6960874 | 0.80 | MEN1 (0.55) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL4853047 | 0.80 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264899-B | 1,3,5-oxadiazine compound and preparation and application thereof | 台州学院 | 2022-06-14 | — | — | CN | disclosed |
| CN-113264899-A | 1,3,5-oxadiazine compound and preparation and application thereof | 台州学院 | 2021-08-17 | — | — | CN | disclosed |
| CN-111533706-B | Preparation method of 1,4, 6-trisubstituted 1, 2-dihydro-triazine compound | 台州学院 | 2021-08-03 | — | — | CN | disclosed |
| CN-111533706-A | Preparation method of 1,4, 6-trisubstituted 1, 2-dihydro-triazine compound | 台州学院 | 2020-08-14 | — | — | CN | disclosed |
| CN-106946790-B | A kind of preparation method of 1,2- substituted benzimidazole analog derivative | 华侨大学 | 2019-08-06 | — | — | CN | disclosed |
| CN-108084110-A | 3- amino benzo [d] isothiazole, derivative and its synthetic method | 湘潭大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-106946790-A | A kind of preparation method of 1,2 substituted benzimidazole analog derivative | 华侨大学 | 2017-07-14 | — | — | CN | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-20040259891-A1 | Novel pyrimidon derivatives | ORCHID CHEMICAL & PHARMACEUTICALS LIMITED (IN) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259891-A1 | Novel pyrimidon derivatives | TYMS, TPMT, TYMP | NPC1 1563/4885RAB9A 2079/4885MEN1 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.