SCHEMBL4862484

SCHEMBL4862484

C=C(C)C(=O)OCCCN1C(=O)C2=C(CCCC2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
ALDH1A1 P00352 6/20 0.39
THRB P10828 1/20 0.38
HTT P42858 2/20 0.38
POLB P06746 2/20 0.38
APEX1 P27695 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
RXFP1 Q9HBX9 1/20 0.34
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
HTR7 P34969 1/20 0.31
LMNA P02545 3/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAPK1 P28482 2/20 0.31
NPC1 O15118 1/20 0.31
NR2F2 P24468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14377607 0.94 TSHR (0.49) TSHRALDH1A1THRBHTTPOLB
SCHEMBL4820861 0.91 THRB (0.40) TSHRALDH1A1THRBHTTPOLB
SCHEMBL15871833 0.88 THRB (0.44) TSHRALDH1A1THRBHTTPOLB
SCHEMBL12922819 0.82 TSHR (0.49) TSHRALDH1A1THRBHTTPOLB
SCHEMBL4864684 0.82 TSHR (0.37) TSHRALDH1A1THRBHTTPOLB
SCHEMBL6270128 0.82 TSHR (0.49) TSHRALDH1A1THRBHTTPOLB
SCHEMBL4861737 0.78 TSHR (0.47) TSHRALDH1A1THRBPOLBRXFP1
SCHEMBL9839694 0.77 SMN1; SMN2 (0.54) TSHRALDH1A1HTTRXFP1KMT2A
SCHEMBL15294289 0.77 TSHR (0.54) TSHRALDH1A1THRBHTTPOLB
SCHEMBL6272348 0.77 TSHR (0.54) TSHRALDH1A1THRBHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8905533-B2 Ink composition and image forming method FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-8905533-B2 Ink composition and image forming method FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-20140313268-A1 AQUEOUS INK COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2014-10-23 US disclosed
US-20140313268-A1 AQUEOUS INK COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2014-10-23 US disclosed
US-20120200653-A1 INK COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2012-08-09 US disclosed
US-7320854-B2 Mixture of oxide particles, polymerizable compound,radiation sensitive decomposer and releasing agent JSR CORPORATION (JP) 2008-01-22 US disclosed
EP-1494072-A2 Radiation sensitive refractive index changing composition, pattern forming method and optical material JSR Corporation (JP) 2005-01-05 EP disclosed
US-20040265737-A1 Radiation sensitive refractive index changing composition, pattern forming method and optical material JSR CORPORATION (JP) 2004-12-30 US disclosed