Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 18/20 | 0.58 |
| ▸ | PPARA | Q07869 | 17/20 | 0.58 |
| ▸ | PPARD | Q03181 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542847 | 0.93 | PGR (0.72) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543002 | 0.93 | PGR (0.81) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543001 | 0.93 | PGR (0.81) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543632 | 0.93 | PGR (0.81) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543186 | 0.92 | PGR (0.63) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543173 | 0.92 | PGR (0.61) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| Calcium SCHEMBL543457 | 0.92 | PGR (0.79) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| Calcium SCHEMBL1336471 | 0.92 | PGR (0.79) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL543589 | 0.92 | PGR (0.79) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL1336464 | 0.92 | PGR (0.79) | PGRADORA3CHRM1TBXA2RPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323491-B2 | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine | CADILA HEALTHCARE LIMITED (IN) | 2008-01-29 | — | — | US | disclosed |
| US-20040186099-A1 | Novel heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine | LOHRAY BRAJ BHUSHAN (IN) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186099-A1 | Novel heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine | CYP11B2, CYP11B1, MAPT | PGR 3233/4885ADORA3 1446/4885CHRM1 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.