⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862460 | 0.88 | SRC (0.31) | — | |
| SCHEMBL4870712 | 0.86 | KDM4E (0.31) | — | |
| SCHEMBL4867355 | 0.78 | KDM4E (0.30) | — | |
| SCHEMBL4861448 | 0.77 | P2RX7 (0.34) | — | |
| SCHEMBL4869256 | 0.76 | SRC (0.31) | — | |
| SCHEMBL4868061 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL4864187 | 0.76 | P2RX7 (0.32) | — | |
| SCHEMBL4866372 | 0.76 | POLB (0.35) | — | |
| SCHEMBL4864460 | 0.75 | — | — | |
| SCHEMBL4862729 | 0.75 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332485-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2008-02-19 | — | — | US | claimed |
| US-20060160802-A1 | Peptide deformylase inhibitors | GLAXO GROUP LIMITED | 2006-07-20 | — | — | US | claimed |
| US-7332485-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2008-02-19 | — | — | US | disclosed |
| US-20060160802-A1 | Peptide deformylase inhibitors | GLAXO GROUP LIMITED | 2006-07-20 | — | — | US | disclosed |