SCHEMBL4863010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4864862	0.90	APP (0.68)	GBA1BCHEACHEAPPPDE5A
	SCHEMBL4866244	0.83	MAPK1 (0.59)	GBA1BCHEACHEAPPMAPK1
	SCHEMBL4866885	0.82	GBA1 (0.59)	GBA1CYP1A2CYP2D6CYP2C19BCHE
	SCHEMBL4859938	0.81	RAD52 (0.69)	GBA1BCHEACHEAPPPDE5A
	SCHEMBL4863857	0.81	PDE5A (0.82)	GBA1PDE5AMAPK1KDM4EKMT2A
	SCHEMBL4865339	0.80	PDE5A (0.80)	GBA1PDE5AMAPK1KDM4EKMT2A
	SCHEMBL4894973	0.78	GBA1 (0.56)	GBA1CYP1A2CYP2D6CYP2C19BCHE
	SCHEMBL4867144	0.78	CCNB2 (0.57)	GBA1CYP1A2CYP2D6CYP2C19BCHE
	SCHEMBL4867595	0.78	APP (0.56)	GBA1CYP1A2CYP2D6CYP2C19BCHE
	SCHEMBL8544714	0.78	APP (0.72)	GBA1CYP1A2CYP2D6CYP2C19BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.