Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.72 |
| ▸ | ACHE | P22303 | 8/20 | 0.72 |
| ▸ | BCHE | P06276 | 6/20 | 0.72 |
| ▸ | CASP6 | P55212 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | RAD52 | P43351 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | UBE2N | P61088 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.63 |
| ▸ | GBA1 | P04062 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747984 | 0.84 | APP (0.76) | APPACHEBCHERAD52MAPT | |
| SCHEMBL11735120 | 0.83 | CASP6 (0.84) | APPACHEBCHECASP6RAD52 | |
| SCHEMBL11734758 | 0.83 | CASP6 (0.62) | APPACHEBCHECASP6RAD52 | |
| SCHEMBL8547756 | 0.81 | APP (0.76) | APPACHEBCHECASP6GBA1 | |
| SCHEMBL21055812 | 0.81 | APP (0.79) | APPACHEBCHECASP6RAD52 | |
| SCHEMBL16280667 | 0.80 | CASP6 (0.92) | APPACHEBCHECASP6RAD52 | |
| SCHEMBL8892633 | 0.80 | RAD52 (0.76) | APPACHEBCHECASP6RAD52 | |
| SCHEMBL23748935 | 0.80 | ACHE (0.68) | APPACHEBCHECASP6RAD52 | |
| SCHEMBL23748931 | 0.80 | ACHE (0.61) | APPACHEBCHECASP6RAD52 | |
| SCHEMBL4866885 | 0.79 | GBA1 (0.59) | APPACHEBCHECASP6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |