Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686904 | 0.85 | KMT2A (0.40) | MAPTKMT2A | |
| SCHEMBL28723828 | 0.82 | MAPT (0.54) | MAPTKMT2A | |
| SCHEMBL27832542 | 0.78 | MAPT (0.50) | MAPTKMT2A | |
| SCHEMBL674112 | 0.76 | MEN1 (0.52) | KMT2A | |
| SCHEMBL9649335 | 0.76 | HCAR2 (0.52) | — | |
| SCHEMBL5674900 | 0.76 | POLB (0.52) | — | |
| SCHEMBL2841832 | 0.76 | CHRNB2 (0.50) | — | |
| SCHEMBL17993295 | 0.74 | MAPT (0.46) | MAPTKMT2A | |
| SCHEMBL28347900 | 0.73 | SIRT2 (0.53) | KMT2A | |
| SCHEMBL27610932 | 0.72 | CHRNB2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |