Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | NPC1 | O15118 | 2/20 | 0.80 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537933 | 1.00 | MAPT (0.80) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL10492259 | 0.89 | MAPT (1.00) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL1315178 | 0.89 | MAPT (1.00) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL6885966 | 0.88 | KMT2A (0.80) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL6886616 | 0.88 | KMT2A (0.80) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL6887177 | 0.88 | MAPT (0.72) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL6886621 | 0.88 | KMT2A (0.80) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL6884868 | 0.86 | KMT2A (0.73) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL6887148 | 0.86 | MAPT (0.73) | MAPTKMT2AMEN1AKR1B1ALDH1A1 | |
| SCHEMBL10492274 | 0.86 | AKR1B1 (0.77) | MAPTKMT2AMEN1AKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7416744-B2 | Extracts, compounds and pharmaceutical compositions having anti-diabetic activity and their use | CONOPCO, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-20060159779-A1 | Extracts, compounds and pharmaceutical compositions having anti-diabetic activity and their use | PHYTOPHARM PLC | 2006-07-20 | — | — | US | disclosed |
| EP-1247809-A2 | Triazine compounds useful as sorbitol dehydrogenase inhibitors | Pfizer Products Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| US-20010051657-A1 | Malonamic acids and derivatives thereof as thyroid receptor ligands | PFIZER INC. | 2001-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060159779-A1 | Extracts, compounds and pharmaceutical compositions having anti-diabetic activity and their use | GANAB, HDAC7, NACA | MAPT 1434/4885KMT2A 4121/4885MEN1 1570/4885 |
| US-20010051657-A1 | Malonamic acids and derivatives thereof as thyroid receptor ligands | THRA, MC1R, THRB | MAPT 2595/4885KMT2A 3863/4885MEN1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.