SCHEMBL4863914

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5103792	0.88	CYP1A2 (0.48)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR
	SCHEMBL5102203	0.88	CYP1A2 (0.64)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR
	SCHEMBL4930371	0.87	APP (0.54)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR
	SCHEMBL4868243	0.87	CYP1A2 (0.51)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR
	SCHEMBL5100498	0.85	CYP1A2 (0.53)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR
	SCHEMBL4864380	0.84	CYP1A2 (0.61)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR
	SCHEMBL4867665	0.84	APP (0.64)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR
	SCHEMBL4866281	0.83	APP (0.52)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR
	SCHEMBL4864516	0.83	APP (0.66)	CYP1A2CYP3A4MEN1KMT2ABCHE
	SCHEMBL4860039	0.83	APP (0.66)	CYP1A2CYP3A4CYP2C19CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.