SCHEMBL4867665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4930371	0.90	APP (0.54)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL4860039	0.88	APP (0.66)	APPSLC2A1EGFRLMNATP53
	SCHEMBL5104358	0.87	APP (0.65)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL4868260	0.86	APP (0.70)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL4864516	0.86	APP (0.66)	APPCYP1A2CYP3A4MEN1KMT2A
	SCHEMBL5102203	0.84	CYP1A2 (0.64)	LMNATP53CYP1A2CYP3A4CYP2D6
	SCHEMBL5100498	0.84	CYP1A2 (0.53)	APPLMNATP53CYP1A2CYP3A4
	SCHEMBL4866281	0.84	APP (0.52)	APPLMNACYP1A2CYP3A4CYP2D6
	SCHEMBL4863914	0.84	CYP1A2 (0.48)	APPLMNATP53CYP1A2CYP3A4
	SCHEMBL4864380	0.82	CYP1A2 (0.61)	SLC2A1LMNATP53CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.