SCHEMBL4864068

SCHEMBL4864068

NC(=O)/C=C\C(=O)NCc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.74
LMNA P02545 2/20 0.74
CYP2D6 P10635 2/20 0.74
CYP2C19 P33261 2/20 0.74
MMP1 P03956 4/20 0.65
MMP2 P08253 4/20 0.65
MMP9 P14780 4/20 0.65
SMN1; SMN2 Q16637 1/20 0.55
CYP2C9 P11712 2/20 0.54
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 2/20 0.52
POLB P06746 1/20 0.52
TAAR1 Q96RJ0 2/20 0.51
CYP1A2 P05177 1/20 0.51
TSHR P16473 1/20 0.51
HTT P42858 1/20 0.49
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4864073 1.00 ALDH1A1 (0.74) ALDH1A1LMNACYP2D6CYP2C19MMP1
SCHEMBL5175679 1.00 ALDH1A1 (0.74) ALDH1A1LMNACYP2D6CYP2C19MMP1
SCHEMBL27311354 0.91 ALDH1A1 (0.89) ALDH1A1LMNACYP2D6CYP2C19MMP1
SCHEMBL10336384 0.91 ALDH1A1 (0.89) ALDH1A1LMNACYP2D6CYP2C19MMP1
SCHEMBL5158355 0.91 ALDH1A1 (0.89) ALDH1A1LMNACYP2D6CYP2C19MMP1
SCHEMBL4021293 0.85 ALDH1A1 (1.00) ALDH1A1LMNACYP2D6CYP2C19MMP1
SCHEMBL4021288 0.85 ALDH1A1 (1.00) ALDH1A1LMNACYP2D6CYP2C19MMP1
SCHEMBL5175917 0.85 ALDH1A1 (1.00) ALDH1A1LMNACYP2D6CYP2C19MMP1
SCHEMBL3658108 0.84 ALDH1A1 (0.61) ALDH1A1LMNACYP2D6CYP2C19MMP1
Acrylamide SCHEMBL28802284 0.81 TGM2 (0.60) ALDH1A1LMNACYP2D6CYP2C19MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7317062-B2 Copolymers, preparation thereof and use as wetting agents and dispersants BYK-CHEMIE GMBH (DE) 2008-01-08 US disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
US-20060069224-A1 Copolymers, preparation thereof and use as wetting agents and dispersants BYK-CHEMIE GMBH (DE) 2006-03-30 US disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
EP-1031414-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-06-16 EP disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
US-6379863-B1 LAMINATING HYDROPHOBIC POLYMER ON SUBSTRATE; HEATING TO MAKE HYDROPHILIC; DURABILITY; REDUCED BLEMISHES; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2002-04-30 US disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
US-6153352-A OBTAINED BY LAMINATING ON A SUBSTRATE A LAYER OF HYDROPHOBIC POLYMER AND A LAYER OF HYDROPHILIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 2000-11-28 US disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed
EP-0922570-A2 Planographic printing plate precursor and a method for producing a planographic plate Fuji Photo Film Co., Ltd. (JP) 1999-06-16 EP disclosed