Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NQO2 | P16083 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858113 | 0.95 | ALDH1A1 (0.50) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| SCHEMBL4858375 | 0.93 | ALDH1A1 (0.49) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| SCHEMBL4859786 | 0.93 | ALDH1A1 (0.49) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL4865034 | 0.92 | ALDH1A1 (0.47) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL4856661 | 0.92 | ALDH1A1 (0.47) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| SCHEMBL29392615 | 0.89 | CYP2C19 (0.45) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| SCHEMBL33660 | 0.89 | CYP2C19 (0.45) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| SCHEMBL6369704 | 0.89 | NQO2 (0.47) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL11438657 | 0.88 | CYP2C19 (0.44) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 | |
| Water SCHEMBL11060635 | 0.88 | CYP2C19 (0.44) | ALDH1A1NQO2CYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | claimed |
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | claimed |
| EP-1568355-A1 | N-alkylhydroxilated secondary paraphenylenediamine which is ortho- and/or meta substituted, composition for dying keratinous fibres comprising this paraphenylenediamine, methods based on this composition and uses. | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
| US-7445645-B2 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | L'OREAL S.A. (FR) | 2008-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026774-A1 | Ortho-and/or meta-substituted N-alkylhydroxylated secondary para-phenylenediamine compounds, compositions for dyeing keratin fibers comprising such compounds, and processes of dyeing therewith | KRT18, CDC73, TYR | ALDH1A1 968/4885NQO2 2173/4885CYP1A2 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.