SCHEMBL33660

SCHEMBL33660

Cc1cc(N)ccc1NCCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.45
MAPT P10636 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
PDE10A Q9Y233 1/20 0.44
ALDH1A1 P00352 2/20 0.43
RAD52 P43351 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
AR P10275 1/20 0.41
VDR P11473 1/20 0.41
BRD4 O60885 1/20 0.40
CASP1 P29466 2/20 0.39
HTT P42858 1/20 0.39
TSHR P16473 1/20 0.39
NQO2 P16083 4/20 0.39
GAA P10253 2/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392615 1.00 CYP2C19 (0.45) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
Water SCHEMBL11060635 0.98 CYP2C19 (0.44) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
Hydrochloric Acid SCHEMBL11438657 0.98 CYP2C19 (0.44) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
Sulfuric Acid SCHEMBL4626210 0.92 MAPT (0.43) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
Sulfuric Acid SCHEMBL11060632 0.91 MAPT (0.42) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
SCHEMBL4862747 0.90 MEN1 (0.44) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
SCHEMBL4864223 0.89 ALDH1A1 (0.44) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
Hydrochloric Acid SCHEMBL4854604 0.89 MEN1 (0.46) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
SCHEMBL4858113 0.88 ALDH1A1 (0.50) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1
SCHEMBL6940255 0.87 CYP2C19 (0.37) CYP2C19MAPTCYP1A2CYP2C9SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2548 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240423887-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2024-12-26 US claimed
EP-4408376-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT Kao Corporation (JP) 2024-08-07 EP claimed
CN-118043022-A Composition comprising a dye and an inorganic alkalizing agent 花王株式会社 2024-05-14 CN claimed
WO-2023054558-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2023-04-06 WO claimed
EP-4159184-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT Kao Corporation (JP) 2023-04-05 EP claimed
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20200392088-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2020-12-17 US claimed
EP-3464247-B1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES OREAL (FR) 2020-03-11 EP claimed
EP-2658507-B1 OXIDATIVE COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2019-04-24 EP claimed
US-8613778-B2 Oxidative colouring composition KAO GERMANY GMBH (DE) 2013-12-24 US claimed
EP-0857478-A2 Oxidative hair dye GOLDWELL GmbH (DE) 1998-08-12 EP claimed
EP-0791352-A2 Hair dyeing composition GOLDWELL GmbH (DE) 1997-08-27 EP claimed
WO-1997010799-A1 OXIDATION DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1997-03-27 WO claimed
US-5421833-A 2-(2'-hydroxyethylamino0-5-aminotoluene and salts as developer and hydroxy compound as coupling agent mixable with peroxide compound immediately before use GOLDWELL AG (DE) 1995-06-06 US claimed
EP-0615743-A1 Hair dyeing composition GOLDWELL GmbH (DE) 1994-09-21 EP claimed
EP-0414585-B1 KERATINOUS FIBRES DYE COMPOSITION CONTAINING AN INDOLE DYE AND AT LEAST A PARAPHENYLENEDIAMINE HAVING A SECONDARY AMINO GROUP AND PROCESS L'OREAL (FR) 1993-04-21 EP claimed
EP-0146350-A2 Hair treatment composition UNILEVER PLC (GB) 1985-06-26 EP claimed
US-4402700-A CONDITIONING CLAIROL INCORPORATED (US) 1983-09-06 US claimed
US-4337061-A NITRO DYES IN AQUEOUS SOLUTION SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-29 US claimed
US-4119399-A AQUEOUS, ALKALINE CLAIROL INCORPORATED (US) 1978-10-10 US claimed