SCHEMBL4864232

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4868215	0.91	PDE5A (0.82)	MEN1KMT2APOLBPDE5AGBA1
	SCHEMBL4863857	0.91	PDE5A (0.82)	MEN1KMT2APOLBPDE5AGBA1
	SCHEMBL4865339	0.90	PDE5A (0.80)	MEN1KMT2APOLBPDE5AGBA1
	SCHEMBL4868103	0.86	PDE5A (0.82)	MEN1KMT2APOLBPDE5AGBA1
	SCHEMBL2583256	0.83	PDE5A (0.90)	MEN1KMT2APOLBPDE5AGBA1
	SCHEMBL16217089	0.82	PDE5A (0.82)	MEN1KMT2APOLBPDE5ASLC2A1
	SCHEMBL4864398	0.82	MEN1 (0.85)	MEN1KMT2APOLBPDE5AGBA1
	SCHEMBL1085431	0.82	PDE5A (1.00)	MEN1KMT2APDE5AGBA1MAPK1
	SCHEMBL18354428	0.81	GBA1 (1.00)	MEN1KMT2APDE5AGBA1MAPK1
	SCHEMBL4913681	0.81	GBA1 (0.71)	MEN1KMT2APOLBPDE5AGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.