SCHEMBL4864398

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4868364	0.88	MEN1 (0.74)	MEN1KMT2AMAPK1POLBSLC2A1
	SCHEMBL16217089	0.86	PDE5A (0.82)	MEN1KMT2AMAPK1POLBSLC2A1
	SCHEMBL16404321	0.85	MAPK1 (0.82)	MEN1KMT2AMAPK1POLBPDE5A
	SCHEMBL4868215	0.85	PDE5A (0.82)	MEN1KMT2AMAPK1POLBSLC2A1
	SCHEMBL3459468	0.85	MAPK1 (0.82)	MEN1KMT2AMAPK1POLBPDE5A
	SCHEMBL14758284	0.83	POLB (0.86)	MEN1KMT2AMAPK1POLBSLC2A1
	SCHEMBL4868103	0.83	PDE5A (0.82)	MEN1KMT2AMAPK1POLBSLC2A1
	SCHEMBL2583256	0.82	PDE5A (0.90)	MEN1KMT2AMAPK1POLBPDE10A
	SCHEMBL4864232	0.82	MEN1 (0.74)	MEN1KMT2AMAPK1POLBSLC2A1
	SCHEMBL1083850	0.82	MAPT (0.69)	MEN1KMT2AMAPK1POLBSLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.