Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036581 | 0.85 | CHRM1 (0.43) | STING1TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL13995182 | 0.84 | LMNA (0.37) | FOLH1TDP1SMN1; SMN2ALDH1A1SLC22A6 | |
| SCHEMBL9668271 | 0.82 | STING1 (0.40) | FOLH1STING1CPA1TDP1CHRM1 | |
| SCHEMBL67494 | 0.82 | FOLH1 (0.56) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL10988160 | 0.80 | FOLH1 (0.43) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL8147756 | 0.80 | FOLH1 (0.52) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL16468366 | 0.79 | FOLH1 (0.52) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL15016034 | 0.78 | — | — | |
| SCHEMBL6468088 | 0.78 | — | — | |
| SCHEMBL139440 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008528252-A | — | — | 2008-07-31 | — | — | JP | claimed |
| EP-1838438-A1 | HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME | Total France (FR) | 2007-10-03 | — | — | EP | claimed |
| WO-2006077326-A1 | HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME | TOTAL FRANCE (FR) | 2006-07-27 | — | — | WO | claimed |
| US-9260459-B2 | 4,6-hexadecadiene-2,4-dicarboxylic acid derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20150183809-A1 | 4,6-HEXADECADIENE-2,4-DICARBOXYLIC ACID DERIVATIVE | KYOWA KIRIN CO., LTD. (JP) | 2015-07-02 | — | — | US | disclosed |
| EP-1838438-B1 | HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME | TOTAL RAFFINAGE FRANCE (FR) | 2014-12-10 | — | — | EP | disclosed |
| EP-1838438-A1 | HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME | Total France (FR) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077326-A1 | HYDROPROCESSING CATALYST, PREPARATION METHOD THEREOF AND USE OF SAME | TOTAL FRANCE (FR) | 2006-07-27 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4460782-A | FUNGICIDES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183809-A1 | 4,6-HEXADECADIENE-2,4-DICARBOXYLIC ACID DERIVATIVE | NR5A2, NR4A3, NR4A2 | FOLH1 2026/4885STING1 4234/4885CPA1 4042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.