Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990336 | 0.95 | SCD (0.38) | SCDAOC3PPARDPPARA | |
| SCHEMBL4988080 | 0.94 | NAMPT (0.36) | SCDAOC3EPHX2NR1H4CHRM4 | |
| SCHEMBL4990577 | 0.94 | SCD (0.38) | SCDAOC3PTPN1RAB9AALDH1A1 | |
| SCHEMBL4985031 | 0.93 | ALDH1A1 (0.42) | SCDRAB9AALDH1A1POLBMAPT | |
| SCHEMBL4988043 | 0.93 | PPARA (0.42) | SCDEPHX2NR1H4CHRM4PPARD | |
| SCHEMBL4988574 | 0.93 | AOC3 (0.43) | SCDAOC3EPHX2NR1H4CHRM4 | |
| SCHEMBL4985430 | 0.91 | AOC3 (0.39) | AOC3RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4991267 | 0.91 | PPARA (0.42) | SCDAOC3ALDH1A1POLBMAPT | |
| SCHEMBL4986164 | 0.91 | AOC3 (0.35) | AOC3PPARA | |
| SCHEMBL4875745 | 0.90 | SCD (0.39) | SCDAOC3RAB9ARXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442715-B2 | Thiazole derivatives | ASTELLAS PHARMA INC. (JP) | 2008-10-28 | — | — | US | disclosed |
| US-20060276521-A1 | Thiazole derivatives | ASTELLAS PHARMA INC. (JP) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276521-A1 | Thiazole derivatives | VCAM1, ICAM1, TXNL1 | SCD 2681/4885AOC3 782/4885PTPN1 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.