SCHEMBL4864973

SCHEMBL4864973

C=C(C)C(=O)OC(F)(CCCC)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
CES2 O00748 4/20 0.33
ALDH1A1 P00352 2/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33
THRB P10828 1/20 0.33
FAAH O00519 8/20 0.32
CES1 P23141 5/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FDPS P14324 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401804 0.93 TSHR (0.49) TSHRCES2LPAR1LPAR3FAAH
SCHEMBL2732937 0.93 TSHR (0.49) TSHRCES2LPAR1LPAR3FAAH
SCHEMBL27462638 0.93 TSHR (0.49) TSHRCES2LPAR1LPAR3FAAH
SCHEMBL5084728 0.93 TSHR (0.49) TSHRCES2LPAR1LPAR3FAAH
SCHEMBL27458125 0.89 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL27892998 0.84 TSHR (0.47) TSHRCES2ALDH1A1LPAR1LPAR3
SCHEMBL27943024 0.83 TSHR (0.45) TSHRCES2LPAR1LPAR3FAAH
SCHEMBL751393 0.83 TSHR (0.45) TSHRCES2LPAR1LPAR3FAAH
SCHEMBL28297656 0.83 TSHR (0.43) TSHRCES2ALDH1A1LPAR1LPAR3
SCHEMBL8520342 0.82 ALDH1A1 (0.38) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102660871-B Fluorine containing water repellent oil repellent composition and its preparation method WUXI HENGCHUANG JIAYE MATERIAL TECHNOLOGY CO LTD 2014-09-03 CN claimed
CN-102660871-A Fluorine containing water repellent oil repellent composition and its preparation method JIANGSU JIAYE FLUORINE MATERIAL TECHNOLOGY CO LTD 2012-09-12 CN claimed
CN-110465468-A The method for forming multilayer film KANSAI PAINT CO LTD 2019-11-19 CN disclosed
CN-109971289-A The damp proof composition of waterproof and its application 东莞东阳光科研发有限公司 2019-07-05 CN disclosed
CN-109351204-A A kind of preparation method and application of fluorine-containing aquagel membrane 济南大学 2019-02-19 CN disclosed
CN-108948939-A A kind of low-k multifunction electronic protective coating composition 黑龙江泰纳科技发展股份有限公司 2018-12-07 CN disclosed
CN-108713046-A Aqueous coating composition 关西涂料株式会社 2018-10-26 CN disclosed
CN-107699099-A A kind of fluorescent visual type electronic protection coating composition and preparation method thereof 浙江大学 2018-02-16 CN disclosed
CN-106029725-A Fluoropolymer structures 大金美国股份有限公司 2016-10-12 CN disclosed
CN-103627285-B The formation method of film and coating-forming agent NODASHI CLIN CO., LTD. (JP) 2016-01-13 CN disclosed
CN-102365339-B Room temperature-curable resin coating composition DAIKIN IND LTD 2015-04-08 CN disclosed
CN-1673295-A Anion electroplating paint and finished articles KANSAI PAINT CO LTD (JP) 2005-09-28 CN disclosed
CN-1637446-A Resin composition for light guide, solidified dry membrane ,light guide and forming method thereof KANSAI PAINT CO LTD (JP) 2005-07-13 CN disclosed
CN-1532005-A Coating method 关西油漆株式会社 2004-09-29 CN disclosed
CN-1161436-C Coating compositions containing a highly fluorinated polymeric additive ��Ļ���Ű˾ 2004-08-11 CN disclosed
CN-1125103-C Coating composition containing highly fluorinated additives having hydroxyl groups DU PONT (US) 2003-10-22 CN disclosed
CN-1402755-A Process for coating thermoplastic substrates with coating composition contg. non-aggressive solvent DU PONT (US) 2003-03-12 CN disclosed
EP-1258509-A1 Solventless polyimide silicone resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-11-20 EP disclosed
CN-1279704-A Coating compositions containing highly fluorinated polymer additives DU PONT (US) 2001-01-10 CN disclosed
CN-1279697-A Coating compositions containing a highly fluorinated hydroxyl containing additive DU PONT (US) 2001-01-10 CN disclosed