SCHEMBL8520342

SCHEMBL8520342

C=C(C)C(=O)OC(F)(CC)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.37
TSHR P16473 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL513355 0.85 THRB (0.33) ALDH1A1THRBTSHR
SCHEMBL27458125 0.85 TSHR (0.38) ALDH1A1THRBTSHR
SCHEMBL4864973 0.82 TSHR (0.43) ALDH1A1THRBTSHR
SCHEMBL18473426 0.80 ALDH1A1 (0.38) ALDH1A1THRBTSHR
SCHEMBL27462638 0.79 TSHR (0.49) TSHR
SCHEMBL2732937 0.79 TSHR (0.49) TSHR
SCHEMBL5084728 0.79 TSHR (0.49) TSHR
SCHEMBL1401804 0.79 TSHR (0.49) TSHR
SCHEMBL27777481 0.78 TSHR (0.36) ALDH1A1THRBTSHR
SCHEMBL3134330 0.76 ALDH1A1 (0.46) ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5855960-A POLYSILICATES; WEATHERPROOFING, ANTISOILANT PROTECTIVECOATING KANSAI PAINT CO., LTD. (JP) 1999-01-05 US disclosed
US-5635572-A ACID-TREATED FILM COMPRISING CURED PRODUCT OF HYDROXYL GROUP-CONTAINING RESIN, POLYISOCYANATE CURING AGENT, ORGANOSILICATE CONDENSATE; STAIN RESISTANCE, WEATHERPROOFING KANSAI PAINT CO., LTD. (JP) 1997-06-03 US disclosed