SCHEMBL4865180

SCHEMBL4865180

CNCc1ccc(CN)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
CYP3A4 P08684 1/20 0.54
MAPT P10636 1/20 0.54
LOXL2 Q9Y4K0 6/20 0.54
TPSAB1 Q15661 3/20 0.50
NOS3 P29474 1/20 0.50
NOS1 P29475 1/20 0.50
NOS2 P35228 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
NCF1 P14598 1/20 0.47
ABAT P80404 1/20 0.46
ADRB2 P07550 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
PSIP1 O75475 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Benzylmethylamine SCHEMBL8215110 0.88 CYP3A4 (0.74) KDM4ECYP3A4MAPTLOXL2NOS1
SCHEMBL24733025 0.87 ST14 (0.61) KDM4ECYP3A4MAPTLOXL2TPSAB1
N-Benzylmethylamine SCHEMBL607789 0.86 MAPT (0.78) KDM4ECYP3A4MAPTLOXL2NOS1
SCHEMBL2504209 0.86 KDM4E (0.68) KDM4ECYP3A4MAPTLOXL2NOS3
N-Benzylmethylamine SCHEMBL8692800 0.84 CYP3A4 (0.68) KDM4ECYP3A4MAPTLOXL2NOS1
Hydrochloric Acid SCHEMBL30925271 0.83 KDM4E (0.74) KDM4ECYP3A4MAPTLOXL2NOS3
SCHEMBL3363042 0.81 NOS1 (0.53) KDM4ECYP3A4MAPTLOXL2NOS3
SCHEMBL30125422 0.81 NOS1 (0.53) KDM4ECYP3A4MAPTLOXL2NOS3
SCHEMBL21675762 0.80 TAAR1 (0.56) KDM4ECYP3A4MAPTLOXL2NOS3
SCHEMBL14864130 0.79 KDM4E (0.42) KDM4ECYP3A4MAPTLOXL2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12319635-B2 Method for producing aromatic aminomethyl MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-06-03 US disclosed
CN-116134012-B Method for producing aminomethyl aromatic 三菱瓦斯化学株式会社 2025-05-13 CN disclosed
EP-4186887-B1 METHOD FOR PRODUCING AROMATIC AMINOMETHYL MITSUBISHI GAS CHEMICAL CO (JP) 2025-02-26 EP disclosed
US-20230265042-A1 METHOD FOR PRODUCING AROMATIC AMINOMETHYL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-08-24 US disclosed
EP-4186887-A1 METHOD FOR PRODUCING AROMATIC AMINOMETHYL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-05-31 EP disclosed
CN-116134012-A Method for producing aminomethyl aromatic 三菱瓦斯化学株式会社 2023-05-16 CN disclosed
WO-2022019105-A1 METHOD FOR PRODUCING AROMATIC AMINOMETHYL 三菱瓦斯化学株式会社 2022-01-27 WO disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
EP-3337481-B1 QUINOLINE-2-AMINE DERIVATIVES AS HUMAN TLR8-SELECTIVE AGONISTS FOR INCREASING IMMUNE RESPONSE UNIV KANSAS (US) 2020-11-11 EP disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
WO-2003032986-A1 2' -METHYL-5-(1,3,4-OXADIAZOL-2-YL)-1,1'-BIPHENYL-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2003-04-24 WO disclosed
EP-0763016-B1 COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS AXYS PHARM INC (US) 2000-01-26 EP disclosed
EP-0558048-B1 Thermoplastic resin composition IDEMITSU PETROCHEMICAL CO (JP) 1999-07-07 EP disclosed
EP-0558047-B1 Copolymer having amino group and process for production thereof DAI ICHI KOGYO SEIYAKU CO LTD (JP) 1998-05-20 EP disclosed
US-5656660-A AMINE OR GUANIDINE GROUP-CONTAINING TRYPTASE INHIBITOR ARRIS PHARMACEUTICAL CORPORATION (US) 1997-08-12 US disclosed
EP-0763016-A1 COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS ARRIS PHARMACEUTICAL CORPORATION (US) 1997-03-19 EP disclosed
US-5552480-A BLEND, IMIDIZED ADDITION POLYMER, ENGINEERING PLASTIC, IMPACT STRENGTH IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1996-09-03 US disclosed
WO-1995032945-A1 COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS ARRIS PHARMACEUTICAL CORPORATION (US) 1995-12-07 WO disclosed
EP-0558047-A2 Copolymer having amino group and process for production thereof DAI-ICHI KOGYO SEIYAKU Co., Ltd. (JP) 1993-09-01 EP disclosed
EP-0558048-A1 Thermoplastic resin composition IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1993-09-01 EP disclosed