Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839459 | 0.87 | ABL1 (0.44) | ABL1RIN1PKMGLO1TACR3 | |
| SCHEMBL4865415 | 0.84 | PKM (0.37) | PKMGLO1MAPTKMT2AMEN1 | |
| SCHEMBL3132617 | 0.82 | ABL1 (0.41) | ABL1RIN1PKMGLO1MAPT | |
| SCHEMBL4404872 | 0.79 | ABL1 (0.46) | ABL1RIN1MAPTKMT2AMEN1 | |
| SCHEMBL4838665 | 0.79 | ABL1 (0.51) | ABL1RIN1PKMGLO1MAPT | |
| SCHEMBL4407963 | 0.74 | ABL1 (0.48) | ABL1RIN1PKMMAPTKDM4E | |
| SCHEMBL4838731 | 0.74 | PKM (0.34) | PKMGLO1TACR3MAPTKMT2A | |
| SCHEMBL4838083 | 0.74 | ABL1 (0.38) | ABL1RIN1GLO1MAPTKMT2A | |
| SCHEMBL4834952 | 0.74 | PKM (0.33) | PKMGLO1MAPTKMT2AMEN1 | |
| SCHEMBL4842968 | 0.72 | MAPT (0.37) | ABL1RIN1MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411065-B2 | Peptide nucleic acid monomers: diphenylmethyl, benzyl, alkylthioalkyl, or phenylthioalkyl esters of N-(1-[4-(2-benzothiazolyl-, 2-benzoxazolyl-, 2-benzofuranyl- or 2-benzothiophenyl-sulfonyl)-3-piperazinon-1-ylcarbonylmethyl]pyrimidon-4-yl)carbamic acids | PANAGENE, INC. (KR) | 2008-08-12 | — | — | US | disclosed |