SCHEMBL4866258

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9921508	0.80	HTT (0.74)	MAPK1EGFRHTTALDH1A1MEN1
	SCHEMBL13844526	0.77	EGFR (0.62)	MAPK1EGFRERBB2HTTMEN1
	SCHEMBL6181626	0.77	MEN1 (1.00)	MAPK1EGFRHTTKDM4EALDH1A1
	SCHEMBL22164645	0.77	HTT (0.81)	MAPK1EGFRERBB2HTTKDM4E
	SCHEMBL14156620	0.77	EGFR (0.62)	MAPK1EGFRERBB2HTTKDM4E
	SCHEMBL13058955	0.76	HDAC3 (0.84)	MAPK1EGFRERBB2
	Hydrochloric Acid SCHEMBL22290778	0.76	EGFR (0.80)	MAPK1EGFRERBB2HTTKDM4E
	SCHEMBL13192098	0.76	EGFR (0.97)	MAPK1EGFRERBB2HTTKDM4E
	Hydrochloric Acid SCHEMBL31429504	0.76	EGFR (0.80)	MAPK1EGFRERBB2HTTKDM4E
	SCHEMBL9921504	0.75	EGFR (0.67)	MAPK1EGFRHTTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.