Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864947 | 1.00 | MTOR (0.44) | MTORALDH1A1GAALCKSMN1; SMN2 | |
| SCHEMBL4865035 | 0.83 | LMNA (0.54) | MTORALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL4865164 | 0.83 | LMNA (0.54) | MTORALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL14159266 | 0.81 | MTOR (0.47) | MTORALDH1A1GAASMN1; SMN2KMT2A | |
| SCHEMBL29715862 | 0.81 | LCK (0.42) | ALDH1A1GAALCKSMN1; SMN2KMT2A | |
| SCHEMBL20703283 | 0.81 | LCK (0.42) | ALDH1A1GAALCKSMN1; SMN2KMT2A | |
| SCHEMBL15006805 | 0.80 | HDAC1 (0.42) | ALDH1A1GAALCKSMN1; SMN2LMNA | |
| SCHEMBL15007072 | 0.80 | CHRNA1 (0.48) | LCKSMN1; SMN2KMT2ALMNA | |
| SCHEMBL4866468 | 0.80 | MTOR (0.37) | MTORKMT2ALMNA | |
| SCHEMBL8279758 | 0.79 | ALDH1A1 (0.51) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384963-B2 | 2′-Methyl-5-(1,3,4-oxadiazol-2-yl)1, 1′-biphenyl-4-carboxaide derivatives and their use as p38 kinase | GLAXO GROUP LIMITED (GB) | 2008-06-10 | — | — | US | disclosed |
| EP-1435949-A1 | 2' -METHYL-5-(1,3,4-OXADIAZOL-2-YL)-1,1'-BIPHENYL-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003032986-A1 | 2' -METHYL-5-(1,3,4-OXADIAZOL-2-YL)-1,1'-BIPHENYL-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-04-24 | — | — | WO | disclosed |