SCHEMBL4866537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4866356	0.87	MAPK1 (0.59)	TSHRALDH1A1USP2MAPK1KDM4E
	SCHEMBL4859009	0.83	LATS1 (0.49)	TSHRALDH1A1LATS1USP2MAPK1
	SCHEMBL8898682	0.81	APP (0.60)	ALDH1A1LATS1MAPK1KDM4ERECQL
	SCHEMBL4938097	0.80	TLR7 (0.51)	TSHRALDH1A1LATS1USP2MAPK1
	SCHEMBL4864697	0.80	MAPK1 (0.73)	TSHRALDH1A1LATS1MAPK1KDM4E
	SCHEMBL4859337	0.79	ACHE (0.50)	LATS1PRNPNPSR1RXFP1MAPK1
	SCHEMBL4866812	0.78	MAPT (0.48)	TSHRALDH1A1LATS1MAPK1KDM4E
	SCHEMBL4863959	0.78	APP (0.67)	MAPK1KDM4EGBA1HTTPDE5A
	SCHEMBL7606516	0.78	LATS1 (0.58)	ALDH1A1LATS1USP2MAPK1KDM4E
	SCHEMBL7606647	0.76	LATS1 (0.79)	TSHRALDH1A1LATS1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.