Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684580 | 1.00 | GABRR1 (0.43) | GABRR1GGT1RNPEPCPB2ENPEP | |
| SCHEMBL2232653 | 0.83 | GABRR1 (0.46) | GABRR1GGT1CPB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL3188611 | 0.83 | GABRR1 (0.46) | GABRR1GGT1CPB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2232656 | 0.83 | GABRR1 (0.46) | GABRR1GGT1CPB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL526345 | 0.82 | GABRR1 (0.45) | GABRR1GGT1CPB2CPB1SMN1; SMN2 | |
| SCHEMBL3470018 | 0.80 | ALDH1A1 (0.52) | GABRR1GGT1ENPEPACEALDH1A1 | |
| SCHEMBL2153099 | 0.80 | GABRR1 (0.43) | GABRR1GGT1CPB2CPB1SMN1; SMN2 | |
| SCHEMBL10721413 | 0.78 | GGT1 (0.42) | GABRR1GGT1CPB2CPB1LMNA | |
| SCHEMBL17292411 | 0.75 | GGT1 (0.43) | GABRR1GGT1CPB2CPB1 | |
| Trifluoroacetic Acid SCHEMBL3611486 | 0.74 | GABRR1 (0.38) | GABRR1GGT1CPB2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402407-B1 | Chemically targeted positional identification of post-translationally phosphorylated peptides | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-07-22 | — | — | US | disclosed |