⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568538 | 0.82 | LMNA (0.43) | — | |
| SCHEMBL1396083 | 0.81 | — | — | |
| SCHEMBL361798 | 0.78 | OR51E2 (0.79) | — | |
| SCHEMBL10983603 | 0.77 | OR51E2 (0.43) | — | |
| SCHEMBL10981171 | 0.77 | OR51E2 (0.43) | — | |
| SCHEMBL10986065 | 0.77 | OR51E2 (0.43) | — | |
| SCHEMBL10977292 | 0.77 | OR51E2 (0.43) | — | |
| SCHEMBL10984944 | 0.77 | OR51E2 (0.43) | — | |
| SCHEMBL10984001 | 0.77 | OR51E2 (0.43) | — | |
| SCHEMBL10988208 | 0.77 | OR51E2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114958934-B | Method for preparing L-glufosinate | 苏州百福安酶技术有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-114958934-A | Method for preparing L-glufosinate-ammonium | 苏州百福安酶技术有限公司 | 2022-08-30 | — | — | CN | claimed |
| EP-1844022-B1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI SCIENCE CO LTD (KR) | 2013-08-14 | — | — | EP | claimed |
| JP-2008525522-A | — | — | 2008-07-17 | — | — | JP | claimed |
| US-20080009509-A1 | Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof | HANMI PHARM CO., LTD (KR) | 2008-01-10 | — | — | US | claimed |
| EP-1844022-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2007-10-17 | — | — | EP | claimed |
| WO-2006071017-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2006-07-06 | — | — | WO | claimed |
| CN-114958934-B | Method for preparing L-glufosinate | 苏州百福安酶技术有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114958934-A | Method for preparing L-glufosinate-ammonium | 苏州百福安酶技术有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-108929336-A | Thiazolopyrimidinone class as the active regulator of nmda receptor | 豪夫迈·罗氏有限公司 | 2018-12-04 | — | — | CN | disclosed |
| CN-105612162-B | Thiazolopyrimidinones as modulators of NMDA receptor activity | 豪夫迈·罗氏有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-108368068-A | Amino Zole derivatives | 帝人制药株式会社 | 2018-08-03 | — | — | CN | disclosed |
| CN-104768554-B | Triazol compound | 霍夫曼-拉罗奇有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104363908-B | pyrrolidinyl heterocyclic | 霍夫曼-拉罗奇有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-105001222-B | 8 [base of 3 amino piperidine 1] Xanthine compounds, its preparation method and purposes as pharmaceutical preparation | 勃林格殷格翰制药两合公司 | 2017-11-07 | — | — | CN | disclosed |
| CN-105612162-A | Thiazolopyrimidinones as modulators of NMDA receptor activity | HOFFMANN LA ROCHE | 2016-05-25 | — | — | CN | disclosed |
| EP-1844022-B1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI SCIENCE CO LTD (KR) | 2013-08-14 | — | — | EP | disclosed |
| US-20080009509-A1 | Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof | HANMI PHARM CO., LTD (KR) | 2008-01-10 | — | — | US | disclosed |
| EP-1844022-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006071017-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2006-07-06 | — | — | WO | disclosed |