SCHEMBL486670

SCHEMBL486670

Cc1cc(Oc2ccc(N)c(C)c2)ccc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.61
ALDH1A1 P00352 8/20 0.54
CYP3A4 P08684 5/20 0.54
TDP1 Q9NUW8 4/20 0.54
TSHR P16473 3/20 0.54
SMN1; SMN2 Q16637 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 4/20 0.46
MEN1 O00255 3/20 0.46
HPGD P15428 1/20 0.46
TEAD4 Q15561 1/20 0.44
GFER P55789 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
POLB P06746 2/20 0.43
MITF O75030 1/20 0.43
GAA P10253 1/20 0.43
NLRP1 Q9C000 1/20 0.43
NOD2 Q9HC29 1/20 0.43
LMNA P02545 1/20 0.43
S100B P04271 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8762387 0.98 NR4A1 (0.58) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL30970172 0.95 NR4A1 (0.56) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL31380 0.95 NR4A1 (0.56) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL9596150 0.91 ALDH1A1 (0.57) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL10350063 0.91 ALDH1A1 (0.61) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL13783384 0.91 NR4A1 (0.58) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL7185516 0.91 ALDH1A1 (0.61) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL31457310 0.91 ALDH1A1 (0.61) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL10353183 0.91 ALDH1A1 (0.58) NR4A1ALDH1A1CYP3A4TDP1TSHR
SCHEMBL6182907 0.89 SMN1; SMN2 (0.52) NR4A1ALDH1A1CYP3A4TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024131943-A1 RESIN COMPOSITION AND USE THEREOF 广东生益科技股份有限公司 2024-06-27 WO claimed
US-9248408-B2 Hollow-fiber element for organic-vapor separation UBE INDUSTRIES, LTD. (JP) 2016-02-02 US claimed
US-20150145106-A1 ELECTRONIC DEVICE MANUFACTURE USING LOW-k DIELECTRIC MATERIALS ASPEN AEROGELS, INC. 2015-05-28 US claimed
US-8080319-B2 Thermosetting resin composition and use thereof Kippon Kayaku Kabushiki Kaisha (JP) 2011-12-20 US claimed
US-20090286087-A1 Thermosetting Resin Composition and Use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-11-19 US claimed
US-7605222-B2 Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-20 US claimed
US-20080194794-A1 MATERIALS FOR THE MANUFACTURE OF PROTON CONDUCTING MEMBRANES, METHODS OF MAKING THE SAME, AND USES THEREOF THE UNIVERSITY OF CONNECTICUT 2008-08-14 US claimed
US-20070043203-A1 Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units GENERAL ELECTRIC COMPANY (US) 2007-02-22 US claimed
US-4568715-A Aromatic polyimide composition comprising mixed solvent UBE INDUSTRIES, LTD. (JP) 1986-02-04 US claimed
US-4069206-A HYGROSCOPIC, PHOTOSENSITIVITY TEIJIN LIMITED (JA) 1978-01-17 US claimed
WO-2024131943-A1 RESIN COMPOSITION AND USE THEREOF 广东生益科技股份有限公司 2024-06-27 WO disclosed
US-20230331915-A1 Isocyanate-Modified Polyimide Resin, Resin Composition and Cured Product of Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2023-10-19 US disclosed
WO-2023187624-A1 ADHESIVE-EQUIPPED METAL SUBSTRATE AND LAMINATE 藤森工業株式会社 2023-10-05 WO disclosed
WO-2023187625-A1 ADHESIVE-ATTACHED METAL SUBSTRATE AND LAMINATE 藤森工業株式会社 2023-10-05 WO disclosed
WO-2023112849-A1 ISOCYANATE-MODIFIED POLYIMIDE RESIN, AND RESIN COMPOSITION CONTAINING SAID ISOCYANATE-MODIFIED POLYIMIDE RESIN AND CURED PRODUCT OF SAME 日本化薬株式会社 2023-06-22 WO disclosed
US-4026871-A Chain-extending phenolic end-capped polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-3998786-A USEFUL FOR PREPARING COATINGS UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-21 US disclosed
US-3996196-A Polyimide-metallo-phthalocyanines and their preparation UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-07 US disclosed
US-3987003-A THERMALLY STABLE DIOXO AND DITHIO-BENZISOQUINOLINE COMPOSITIONS AND PROCESS OF SYNTHESIZING SAME THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-10-19 US disclosed
US-3960980-A Method of producing elastomer resins BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-06-01 US disclosed