Chloromethane

Chloromethane

SCHEMBL4866738

C=Cc1ccncc1.CCl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 1/20 0.43
HDAC8 Q9BY41 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
CYP1A2 P05177 2/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 1/20 0.40
ALOX15 P16050 1/20 0.40
CASP1 P29466 1/20 0.40
HBB P68871 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
JUN P05412 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14867 0.92
SCHEMBL28222778 0.92 ALDH1A1 (0.59) ALDH1A1TSHRHDAC8SMN1; SMN2MAPT
Methyl Alcohol SCHEMBL28761443 0.90 ALDH1A1 (0.50) ALDH1A1TSHRHDAC8SMN1; SMN2MAPT
Propene SCHEMBL28134985 0.90 ALDH1A1 (0.50) ALDH1A1TSHRHDAC8SMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL220696 0.89
SCHEMBL9405395 0.89
SCHEMBL9693194 0.89
Bromide SCHEMBL3107187 0.89 ALDH1A1 (0.56) ALDH1A1TSHRHDAC8SMN1; SMN2MAPT
SCHEMBL1462870 0.89
SCHEMBL8609621 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6712949-B2 EMPLOYING REDOX CATALYSTS IN GAS DIFFUSION ELECTRODE OR MEMBRANE ELECTRODE ASSEMBLY IN SEMI-CHEMICAL/ELECTROCHEMICAL SYSTEM FOR PRODUCTION OF HIGH PURITY, STABLE AQUEOUS SOLUTIONS OF PEROXIDE AT HIGH EFFICIENCIES THE ELECTROSYNTHESIS COMPANY, INC. 2004-03-30 US claimed
WO-2003010360-A1 ELECTROCHEMICAL SYNTHESIS OF HYDROGEN PEROXIDE THE ELECTROSYNTHESIS COMPANY, INC. (US) 2003-02-06 WO claimed
CN-115326901-B Nanopore sequencer 伊鲁米纳公司 2024-03-01 CN disclosed
CN-115326901-A Nanopore sequencer 伊鲁米纳公司 2022-11-11 CN disclosed
CN-111247428-B Nanopore sequencer 伊鲁米纳公司 2022-08-23 CN disclosed
CN-111247428-A Nanopore sequencer 伊鲁米纳公司 2020-06-05 CN disclosed
US-7456322-B2 Process for preparing 1,3-dibromoacetone, 1-3-dichloroacetone and epichlorohydrin DOW GLOBAL TECHNOLOGIES INC. (US) 2008-11-25 US disclosed
US-20080249324-A1 Process For Preparing 1,3-Dibromoacetone, 1-3-Dichloroacetone and Epichlorohydrin DAVIS CLARK S 2008-10-09 US disclosed
US-7388019-B2 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes MERCK & CO., INC. (US) 2008-06-17 US disclosed
EP-1758843-A2 PROCESS FOR PREPARIING 1,3-DIBROMOACETONE, 1-3-DICHLOROACETONE AND EPICHLOROHYDRIN Dow Gloval Technologies Inc. (US) 2007-03-07 EP disclosed
US-20060074087-A1 3-Amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes MERCK SHARP & DOHME LLC 2006-04-06 US disclosed
WO-2005115954-A2 PROCESS FOR PREPARIING 1,3-DIBROMOACETONE, 1-3-DICHLOROACETONE AND EPICHLOROHYDRIN DOW GLOBAL TECHNOLOGIES INC. (US) 2005-12-08 WO disclosed
US-6712949-B2 EMPLOYING REDOX CATALYSTS IN GAS DIFFUSION ELECTRODE OR MEMBRANE ELECTRODE ASSEMBLY IN SEMI-CHEMICAL/ELECTROCHEMICAL SYSTEM FOR PRODUCTION OF HIGH PURITY, STABLE AQUEOUS SOLUTIONS OF PEROXIDE AT HIGH EFFICIENCIES THE ELECTROSYNTHESIS COMPANY, INC. 2004-03-30 US disclosed
US-20030019758-A1 Electrochemical synthesis of hydrogen peroxide THE ELECTROSYNTHESIS COMPANY, INC. 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060074087-A1 3-Amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes DPP4, DPP3, DPP7 ALDH1A1 686/4885TSHR 4488/4885HDAC8 2888/4885
US-20080249324-A1 Process For Preparing 1,3-Dibromoacetone, 1-3-Dichloroacetone and Epichlorohydrin DBN1, GNPAT, HKDC1 ALDH1A1 692/4885TSHR 4178/4885HDAC8 2347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.